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Multiparametric CEST and Z-spectrum analysis proton (ZAP) as biomarkers of human brain aging

Abstract Chemical exchange saturation transfer (CEST) has been investigated to capture specific hydroxyl, amine, and amide protons. Z-spectrum analysis protons (ZAP) technique quantifies relaxation times of relatively free- ( $$\:{T}_{\:\:2,f}^{ex}$$ ) and restricted exchange proton ( $$\:{T}_{\:\:2...

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Auteurs principaux: Hye Na Jung, Vadim Malis, Mitsue Miyazaki
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2026-04-01
Collection:Scientific Reports
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Accès en ligne:https://doi.org/10.1038/s41598-026-46623-6
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