YBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells

The understanding of molecular mechanisms in different subtypes of head and neck cancer (HNC) will define subtype-specific treatment options. Here the authors show that PI3K-phospho-YBX1 axis promotes tumour growth in basal subtype of HNC, while unphosphorylated YBX1 acts as a suppressor of metastas...

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Autori principali:	Yuchen Bai, Carolin Gotz, Ginevra Chincarini, Zixuan Zhao, Clare Slaney, Jarryd Boath, Luc Furic, Christopher Angel, Stephen M. Jane, Wayne A. Phillips, Steven A. Stacker, Camile S. Farah, Charbel Darido
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2023-03-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-023-37161-0
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