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Both the C-terminal polylysine region and the farnesylation of K-RasB are important for its specific interaction with calmodulin.

BACKGROUND: Ras protein, as one of intracellular signal switches, plays various roles in several cell activities such as differentiation and proliferation. There is considerable evidence showing that calmodulin (CaM) binds to K-RasB and dissociates K-RasB from membrane and that the inactivation of C...

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Detaylı Bibliyografya
Asıl Yazarlar: Ling-Jia Wu, Li-Rong Xu, Jun-Ming Liao, Jie Chen, Yi Liang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2011-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC3130059?pdf=render
Etiketler: Etiketle
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