Inhibition of IkappaB kinase by vaccinia virus virulence factor B14.
The IkappaB kinase (IKK) complex is a key regulator of signal transduction pathways leading to the induction of NF-kappaB-dependent gene expression and production of pro-inflammatory cytokines. It therefore represents a major target for the development of anti-inflammatory therapeutic drugs and may...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2008-02-01
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| Serier: | PLoS Pathogens |
| Online adgang: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0040022&type=printable |
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