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The role of glutathione peroxidase 4 in neuronal ferroptosis and its therapeutic potential in ischemic and hemorrhagic stroke

Ferroptosis is a type of cell death that depends on iron and is driven by lipid peroxidation, playing a crucial role in neuronal death during stroke. A central element in this process is the inactivation of glutathione peroxidase 4 (GPx4), an antioxidant enzyme that helps maintain redox balance by r...

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Autor principal: Chao Wei
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2024-10-01
Col·lecció:Brain Research Bulletin
Matèries:
Accés en línia:http://www.sciencedirect.com/science/article/pii/S0361923024001990
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