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One step derivatization and switchable hydrophilicity solvent-based microextraction for the determination of adamantane analogues in human urine by HPLC-FLD

The present study describes an “one-step” derivatization and microextraction using a pH-switchable hydrophilicity solvent for the determination of amantadine and memantine in human urine by liquid chromatography and fluorescence detection. The procedure is based on the derivatization of the analytes...

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Principais autores: Marianna Ntorkou, Paraskevas D. Tzanavaras, Constantinos K. Zacharis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-10-01
coleção:Advances in Sample Preparation
Assuntos:
Switchable hydrophilicity solvent
Derivatization
Microextraction
Amantadine
Memantine
Liquid chromatography
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2772582024000330
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