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Blood vessel tortuosity selects against evolution of aggressive tumor cells in confined tissue environments: A modeling approach.

Cancer is a disease of cellular regulation, often initiated by genetic mutation within cells, and leading to a heterogeneous cell population within tissues. In the competition for nutrients and growth space within the tumors the phenotype of each cell determines its success. Selection in this proces...

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Bibliografske podrobnosti
Principais autores: András Szabó, Roeland M H Merks
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2017-07-01
Serija:PLoS Computational Biology
Online dostop:http://europepmc.org/articles/PMC5536454?pdf=render
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