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Inhibitor of bromodomain and extraterminal domain proteins decreases transcription of Cd33 in the brain of mice subjected to systemic inflammation; a promising strategy for neuroprotection

The neuroinflammation is a crucial component of virtually all neurodegenerative disorders, including Alzheimer’s disease (AD). The bacterial lipopolysaccharide (LPS), a potent activator of the innate immune system, was suggested to influence or even trigger the neuropathological alterations in AD. L...

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Bibliografiske detaljer
Principais autores: Grzegorz A. Czapski, Marta Matuszewska, Magdalena Cieślik, Joanna B. Strosznajder
Format: Artigo
Sprog:Inglês
Udgivet: Termedia Publishing House 2024-05-01
Serier:Folia Neuropathologica
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