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Peptidyl-tRNA Hydrolase Screening Combined with Molecular Docking Reveals the Antibiotic Potential of Bark Extract

With the rapid rise of antibiotic resistance in pathogenic bacteria, the need for new antibacterial agents is overwhelming. Herein we report the limited screening of tropical plant extracts for inhibitory activity against the essential enzyme peptidyl-tRNA hydrolase (Pth). Initial screening was cond...

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Detalhes bibliográficos
Principais autores: Sarah M. Harris, Hana McFeeters, Ifedayo V. Ogungbe, Luis R. Cruz-Vera, William N. Setzer, Betsy R. Jackes, Robert L. McFeeters
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2011-10-01
coleção:Natural Product Communications
Acesso em linha:https://doi.org/10.1177/1934578X1100601003
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