Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp
Bacterial responses to nutrient limitation and other stress conditions are often modulated by the nucleotide-based second messenger (p)ppGpp. Here, the authors show that (p)ppGpp inhibits the SRP membrane-protein insertion and secretion pathway by binding to GTPases Ffh and FtsY.
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2022-02-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-022-28675-0 |
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