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IL-1R/C3aR signaling regulates synaptic pruning in the prefrontal cortex of depression

Abstract Background Major depressive disorder is characterized by not only monoamine neurotransmitters deficiencies but also persistent neuroinflammation. The complement system is an attractive therapeutic target for various inflammation-related diseases due to its early activation in inflammatory p...

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Bibliografische Detailangaben
Hauptverfasser: Man-Man Zhang, Min-Xia Guo, Qiu-Ping Zhang, Xue-Qin Chen, Na-Zhi Li, Qing Liu, Jie Cheng, Shi-Le Wang, Guang-Hui Xu, Cheng-Fu Li, Ji-Xiao Zhu, Li-Tao Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-06-01
Schriftenreihe:Cell & Bioscience
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Online-Zugang:https://doi.org/10.1186/s13578-022-00832-4
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