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Proteomic characterization of Helicobacter pylori CagA antigen recognized by child serum antibodies and its epitope mapping by peptide array.

Serum antibodies against pathogenic bacteria play immunologically protective roles, and can be utilized as diagnostic markers of infection. This study focused on Japanese child serum antibodies against Helicobacter pylori, a chronically-infected gastric bacterium which causes gastric cancer in adult...

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Principais autores: Junko Akada, Masumi Okuda, Narumi Hiramoto, Takao Kitagawa, Xiulian Zhang, Shuichi Kamei, Akane Ito, Mikiko Nakamura, Tomohisa Uchida, Tomoko Hiwatani, Yoshihiro Fukuda, Teruko Nakazawa, Yasuhiro Kuramitsu, Kazuyuki Nakamura
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4139317?pdf=render
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