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Relationship between hippocampal volume and treatment response before and after escitalopram administration in patients with depression

Abstract The hippocampus plays a crucial role in memory formation and emotional regulation, and is closely related to the pathology of depression. Escitalopram, a selective serotonin reuptake inhibitor, promotes neurogenesis in the dentate gyrus of the hippocampus and alters its structure. This stud...

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Bibliografiske detaljer
Principais autores: Toshiharu kamishikiryo, Eri itai, Yuki mitsuyama, Yoshikazu masuda, Osamu yamamoto, Tatsuji tamura, Hiroaki jitsuiki, Akio mantani, Norio yokota, Go okada
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2025-12-01
Serier:Translational Psychiatry
Online adgang:https://doi.org/10.1038/s41398-025-03796-4
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