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Tight Complex Formation of the Fumarate Sensing DcuS-DcuR Two-Component System at the Membrane and Target Promoter Search by Free DcuR Diffusion

ABSTRACT Signaling of two-component systems by phosphoryl transfer requires interaction of the sensor kinase with the response regulator. Interaction of the C4-dicarboxylate-responsive and membrane-integral sensor kinase DcuS with the response regulator DcuR was studied. In vitro, the cytoplasmic pa...

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Autori principali: Stefaniya Gencheva, Simon Dersch, Kristin Surmann, Mathias Wernet, Luis Antelo, Elke Hammer, Peter L. Graumann, Nadja Hellmann, Gottfried Unden
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2022-08-01
Serie:mSphere
Soggetti:
sensor kinase
two-component system
sensor complex
complex formation
bacteria
DcuS-DcuR
Accesso online:https://journals.asm.org/doi/10.1128/msphere.00235-22
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