Tumor cell cytoplasmic metallothionein expression associates with differential tumor immunogenicity and prognostic outcome in high-grade serous ovarian carcinoma

BackgroundThe underlying mechanism of high T-cell presence as a favorable prognostic factor in high-grade serous ovarian carcinoma (HGSOC) is not yet understood. In addition to immune cells, various cofactors are essential for immune processes. One of those are metallothioneins (MTs), metal-binding...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Elena Mairinger, Michael Wessolly, Paul Buderath, Sabrina Borchert, Larissa Henrich, Pawel Mach, Julia Steinborn, Rainer Kimming, Bharat Jasani, Kurt Werner Schmid, Agnes Bankfalvi, Fabian Dominik Mairinger
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2023-11-01
Rangatū:	Frontiers in Oncology
Ngā marau:	high-grade serous ovarian carcinoma metallothionein overall survival immune response zinc signaling
Urunga tuihono:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1252700/full
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