Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC.

<h4>Background</h4>Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein (vFLIP) K13 activates the NF-κB pathway by binding to the NEMO/IKKγ subunit of the IκB kinase (IKK) complex. However, it has remained enigmatic how K13-NEMO interaction results in the activation of the...

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Principais autores:	Hittu Matta, Ramakrishnan Gopalakrishnan, Ciaren Graham, Bhairavi Tolani, Akshat Khanna, Han Yi, Yulan Suo, Preet M Chaudhary
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2012-01-01
Serier:	PLoS ONE
Online adgang:	https://doi.org/10.1371/journal.pone.0036601
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