Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1

Antibodies targeting non-structural protein 1 (NS1) confer protection against Zika virus (ZIKV). Although monoclonal antibodies (MAbs) 3G2 and 4B8 are more potent than MAb 4F10 in suppressing ZIKV infection in neonatal mice models, the epitopes are unclear. Herein, we determined the Cryo-electron mi...

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Bibliographic Details

Main Authors:	Qi Pan, Xiaomin Xing, Jianhai Yu, Qiang Chen, Haizhan Jiao, Wanqin Zhang, Yingfen Wen, Ming Gao, Wei Zhao, Lei Yu, Hongli Hu
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2024-10-01
Series:	hLife
Subjects:	Zika virus (ZIKV) non-structural protein 1 (NS1) monoclonal antibodies (MAbs) epitopes
Online Access:	http://www.sciencedirect.com/science/article/pii/S2949928324000427
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