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Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity

Abstract Background Interactions between the gut microbiota, diet, and host metabolism contribute to the development of cardiovascular disease, but a firm link between disease-specific gut microbiota alterations and circulating metabolites is lacking. Methods We performed shot-gun sequencing on 235...

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Furkejuvvon:
Váldodahkkit: Sajan C. Raju, Antonio Molinaro, Ayodeji Awoyemi, Silje F. Jørgensen, Peder R. Braadland, Andraz Nendl, Ingebjørg Seljeflot, Per M. Ueland, Adrian McCann, Pål Aukrust, Beate Vestad, Cristiane Mayerhofer, Kaspar Broch, Lars Gullestad, Knut T. Lappegård, Bente Halvorsen, Karsten Kristiansen, Johannes R. Hov, Marius Trøseid
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2024-02-01
Ráidu:Genome Medicine
Fáttát:
Imidazole propionate
Gut microbiota
Inflammation
Heart failure
Liŋkkat:https://doi.org/10.1186/s13073-024-01296-6
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