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Expression of BNIP3 in invasive breast cancer: correlations with the hypoxic response and clinicopathological features

<p>Abstract</p> <p>Background</p> <p>Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) is a pro-apoptotic member of the Bcl-2 family induced under hypoxia. Low or absent expression has recently been described in human tumors, including gastrointestinal tumors, resulting in poor prognosis. Li...

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Bibliographic Details
Main Authors: de Weger Roel A, van Wichen Dick F, van Laar Theo, Koop Esther A, Wall Elsken, van Diest Paul J
Format: Artigo
Language:Inglês
Published: BMC 2009-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/175
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