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Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Abstract Background Chemotherapeutics can stimulate immune antitumor response by inducing immunogenic cell death (ICD), which is activated by Damage-Associated Molecular Patterns (DAMPs) like the exposure of calreticulin (CRT) on the cell surface, the release of ATP and the secretion of High Mobilit...

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Principais autores: José Ignácio Gonzalez Solari, Eduardo Filippi-Chiela, Emily Salles Pilar, Vitória Nunes, Esteban Alberto Gonzalez, Fabrício Figueiró, Cristiano Feijó Andrade, Fábio Klamt
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-05-01
Serier:BMC Cancer
Fag:
Non-small cell lung carcinoma (NSCLC)
Damage-associated molecular patterns (DAMPs)
Immunogenic cell death (ICD)
Autophagy
Cisplatin
Etoposide
Online adgang:http://link.springer.com/article/10.1186/s12885-020-06964-5
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