Polygenic scores and antidepressant treatment outcomes in major depression: a critical integrative review

Major depressive disorder (MDD) shows a large heterogeneity in antidepressant treatment outcome, a variability explained in part by common-variant liability captured by polygenic scores (PGSs). We performed a review of PubMed- and Google Scholar-indexed studies that related any PGS to treatment resp...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Alessandro Serretti, Chiara Fabbri, Giuseppe Fanelli, Bernhard T. Baune, Alessandra Minelli, Mara Dierssen, Eduard Maron, Marie-Claude Potier, Massimo Gennarelli, Roos van Westrhenen, Alessio Squassina, Divja Mehta, Joost G.E. Janzing, Evelien van Assche, Georgios Schoretsanitis, Pietro Lio’, Filip Rybakowski, Claudia Pisanu
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2025-01-01
Σειρά:	Neuroscience Applied
Θέματα:	Major depression Antidepressants Polygenic risk scores Treatment resistant depression Treatment outcomes Genome-wide association studies (GWASs)
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S277240852500122X
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