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Toxic Effects of Methotrexate on Rat Kidney Recovered by Crocin as a Consequence of Antioxidant Activity and Lipid Peroxidation Prevention

Background: The application of methotrexate (MTX) as a chemotherapy agent and immune system suppressant has various side effects. Crocin, a xanthine derivative plant, has many therapeutic benefits. This study was planned to assess the effect of crocin on renal toxicity of MTX in a rat model. Methods...

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Detalhes bibliográficos
Principais autores: Cyrus Jalili, Ali Ghanbari, Shiva Roshankhah, Mohammad Reza Salahshoor
Formato: Artigo
Idioma:Inglês
Publicado em: Pasteur Institute of Iran 2020-01-01
coleção:Iranian Biomedical Journal
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Acesso em linha:http://ibj.pasteur.ac.ir/article-1-2868-en.html
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