Study of RNA interference inhibiting rat ovarian androgen biosynthesis by depressing 17alpha-hydroxylase/17, 20-lyase activity in vivo
<p>Abstract</p> <p>Background</p> <p>17alpha-hydroxylase/17, 20-lyase encoded by CYP17 is the key enzyme in androgen biosynthesis pathway. Previous studies demonstrated the accentuation of the enzyme in patients with polycystic ovary syndrome (PCOS) was the most important mechanism of androgen exces...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2009-07-01
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| Seria: | Reproductive Biology and Endocrinology |
| Dostęp online: | http://www.rbej.com/content/7/1/73 |
| Etykiety: |
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