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131 genetic loci highlight immunological pathways and tissues in nasal polyposis and asthma

Abstract The coexistence of asthma and chronic rhinosinusitis with nasal polyposis (CRSwNP) is associated with allergic phenotypes, disease severity and failure of first-line treatment for both asthma and CRSwNP. Recent studies have highlighted shared genetic components for these diseases. To better...

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Principais autores: Elmo C. Saarentaus, Kasper Fischer-Rasmussen, Eeva Sliz, Argyro Bizaki-Vallaskangas, FinnGen, Tarja Laitinen, Sanna Toppila-Salmi, Hannu Kankaanranta, Johannes Kettunen, Klaus Bønnelykke, Aarno Palotie, Antti Mäkitie
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2025-11-01
Serija:Nature Communications
Online dostop:https://doi.org/10.1038/s41467-025-64847-4
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