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Retained avidity despite reduced cross-binding and cross-neutralizing antibody levels to Omicron after SARS-COV-2 wild-type infection or mRNA double vaccination

IntroductionThe rapid evolution of SARS-CoV-2 has posed a challenge to long-lasting immunity against the novel virus. Apart from neutralizing function, binding antibodies induced by vaccination or infection play an important role in containing the infection. MethodsTo determine the proportion of wil...

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Autori principali: Teresa Harthaller, Barbara Falkensammer, David Bante, Maria Huber, Melanie Schmitt, Habib Benainouna, Annika Rössler, Verena Fleischer, Dorothee von Laer, Janine Kimpel, Reinhard Würzner, Wegene Borena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-07-01
Serie:Frontiers in Immunology
Soggetti:
COVID-19
binding antibodies
avidity
mutation
humoral immunity
convalescent
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1196988/full
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