Long-term glucocorticoid treatment increases CD204 expression by activating the MAPK pathway and enhances modified LDL uptake in murine macrophages

Atherosclerotic plaques develop from the accumulation of macrophage-derived foam cells via the uptake of modified low-density lipoprotein (LDL). CD36 and CD204 are the principal scavenger receptors responsible for the uptake of modified LDL. Although glucocorticoids are suspected to exacerbate ather...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ryota Hashimoto, Hiroshi Koide, Youichi Katoh
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-01-01
Schriftenreihe:	Journal of Pharmacological Sciences
Schlagworte:	Atherosclerosis Glucocorticoids Scavenger receptors Uptake of modified LDL MAPK pathway
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S134786132200086X
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