Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedside

Abstract Proprotein convertase subtilisin/kexin type 9 (PCSK9) has evolved as a pivotal enzyme in lipid metabolism and a revolutionary therapeutic target for hypercholesterolemia and its related cardiovascular diseases (CVD). This comprehensive review delineates the intricate roles and wide-ranging...

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Principais autores:	Xuhui Bao, Yongjun Liang, Hanman Chang, Tianji Cai, Baijie Feng, Konstantin Gordon, Yuekun Zhu, Hailian Shi, Yundong He, Liyi Xie
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2024-01-01
Serija:	Signal Transduction and Targeted Therapy
Online dostop:	https://doi.org/10.1038/s41392-023-01690-3
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