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The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson’s disease

Abstract The objective of this study was to investigate the association between a Parkinson’s disease (PD)-specific polygenic score (PGS) and protective lifestyle factors on age at onset (AAO) in PD. We included data from 4367 patients with idiopathic PD, 159 patients with GBA1-PD, and 3090 healthy...

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Autors principals: Carolin Gabbert, Leonie Blöbaum, Theresa Lüth, Inke R. König, Amke Caliebe, Sebastian Sendel, Björn-Hergen Laabs, Christine Klein, Joanne Trinh
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2024-06-01
Col·lecció:Scientific Reports
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Accés en línia:https://doi.org/10.1038/s41598-024-65640-x
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