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Elevation of ISG15 promotes diabetic kidney disease by modulating renal tubular epithelial cell pyroptosis

Abstract Background Fibrosis and inflammation in the renal tubular epithelial cells (TECs) are key contributors to the pathology of diabetic kidney disease (DKD). Nevertheless, the precise triggers of these processes remain unclear. This study aimed to explore the role of interferon‐stimulated gene...

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Hlavní autoři: Lingzhi Huang, Xinyi Chen, Yawen Shao, Shujun Deng, Chen Wang, Jianqiao Chen, Yongsheng Xie, Siming Yuan, Liqin Tang
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2025-06-01
Edice:Clinical and Translational Medicine
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On-line přístup:https://doi.org/10.1002/ctm2.70337
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