Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy

Background Fms-like tyrosine kinase-3 (FLT3) gene mutations are frequent in acute promyelocytic leukemia but their prognostic value is not well established.Design and Methods We evaluated FLT3-internal tandem duplication and FLT3-D835 mutations in patients treated with all-trans retinoic acid and an...

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Библиографические подробности

Главные авторы:	Eva Barragán, Pau Montesinos, Mireia Camos, Marcos González, Maria J. Calasanz, José Román-Gómez, Maria T. Gómez-Casares, Rosa Ayala, Javier López, Óscar Fuster, Dolors Colomer, Carmen Chillón, María J. Larrayoz, Pedro Sánchez-Godoy, José González-Campos, Félix Manso, Maria L. Amador, Edo Vellenga, Bob Lowenberg, Miguel A. Sanz
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Ferrata Storti Foundation 2011-10-01
Серии:	Haematologica
Online-ссылка:	https://haematologica.org/article/view/6094
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