Insulin receptor substrate 1 is a novel member of EGFR signaling in pancreatic cells

Pancreatic ductal adenocarcinoma is an extremely incurable cancer type characterized by cells with highly proliferative capacity and resistance against the current therapeutic options. Our study reveals that IRS1 acts as a bridging molecule between EGFR and IGFR/InsR signalization providing a potent...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Tamás Takács, Loretta László, Álmos Tilajka, Julianna Novák, László Buday, Virag Vas
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2024-12-01
Sarja:	European Journal of Cell Biology
Aiheet:	EGF EGF receptor IRS1 GRB2 Pancreatic adenocarcinoma Signaling crosstalk
Linkit:	http://www.sciencedirect.com/science/article/pii/S0171933524000748
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