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Motor neuron survival is associated with reduced neuroinflammation and increased autophagy after brachial plexus avulsion injury in aldose reductase-deficient mice

Abstract Brachial plexus root avulsion (BPRA) is frequently caused by high-energy trauma including traffic accident and birth trauma, which will induces massive motoneurons (MNs) death as well as loss of motor and sensory function in the upper limb. The death of MNs is attributed to energy deficienc...

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Principais autores: Ke Zhong, Yu Huang, Prince last Mudenda Zilundu, Yaqiong Wang, Yingying Zhou, Guangyin Yu, Rao Fu, Sookja Kim Chung, Yamei Tang, Xiao Cheng, Lihua Zhou
Format: Artigo
Jezik:Inglês
Izdano: BMC 2022-11-01
Serija:Journal of Neuroinflammation
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Online dostop:https://doi.org/10.1186/s12974-022-02632-6
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