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Discovery of diphenyl ethers as novel inhibitors of insect trehalase via virtual screening and biological assays

Trehalase hydrolyzes trehalose to glucose to provide energy for insects or building blocks for chitin synthesis. Because trehalase is critical to insects but not to humans, it has long been considered a promising target for green insecticides. However, the known trehalase inhibitors are mainly sugar...

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Hlavní autoři: Xi Jiang, Wenda Li, Qiong Lu, Yi Ding, Mingjia Gao, Shanru He, Wei Liu, Yong Zhou, Tian Liu
Médium: Artigo
Jazyk:Inglês
Vydáno: KeAi Communications Co., Ltd. 2025-12-01
Edice:Advanced Agrochem
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2773237124001060
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