Identification of prognostic signatures in pheochromocytomas and paragangliomas based on mitochondrial autophagy and ferroptosis in TCGA and GEO datasets

Abstract Pheochromocytomas (PCCs) and paragangliomas (PGLs), collectively PPGLs, are rare tumors with significant molecular heterogeneity, which complicates prognosis and treatment. This study analyzed publicly available datasets (TCGA-PPGLs, GSE19422, GSE60459) to identify differentially expressed...

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Autori principali:	Qingke Chen, Zhiyong Xian, Qian Zou, Junming Bi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2026-01-01
Serie:	Discover Oncology
Soggetti:	Pheochromocytomas (PCCs) Paragangliomas (PGLs) Mitochondrial autophagy Ferroptosis Prognostic risk model
Accesso online:	https://doi.org/10.1007/s12672-026-04393-7
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