Comparative risk of systemic autoimmune diseases in juvenile idiopathic arthritis treated with TNF-α or IL-6 inhibitors: a real-world cohort study

ObjectiveThis study aimed to compare the risk of developing systemic autoimmune diseases (SADs) among pediatric patients with juvenile idiopathic arthritis (JIA) treated with tumor necrosis factor inhibitors (TNFi) versus interleukin-6 inhibitors (IL-6i), based on real-world data.MethodsWe conducted...

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Autori principali:	Jih-Jin Tsai, Li-Teh Liu, Ping-Chang Lin, Yu-Hsun Wang, Yung-Heng Lee, James Cheng-Chung Wei
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-01-01
Serie:	Frontiers in Immunology
Soggetti:	interleukin-6 inhibitors juvenile idiopathic arthritis pediatric systemic autoimmune diseases tumor necrosis factor inhibitors
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1744226/full
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