Contributions of DNA mechanics and trans-regulation to nucleosome positioning in Schizosaccharomyces pombe and its role in co-transcriptional splicing

Abstract Background Nucleosome positioning critically regulates chromatin functions, yet species-specific mechanisms remain incompletely understood. This study revisits nucleosome organization in Schizosaccharomyces pombe  ( S. pombe) using a DNA deformation energy model and a high-resolution nucleo...

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Autors principals:	Guoqing Liu, Jing Cang, Zhihao Du, Xiangjun Cui, Hongyu Zhao, Jia Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-04-01
Col·lecció:	Epigenetics & Chromatin
Matèries:	DNA deformation energy Rotational positioning Gene expression Splice site 3D genome
Accés en línia:	https://doi.org/10.1186/s13072-026-00675-0
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