Development of In Vitro Potency Methods to Replace In Vivo Tests for Enterovirus 71 Inactivated Vaccine (Human Diploid Cell-Based/Vero Cell-Based)

Background: The three commercial Enterovirus 71 (EV71) inactivated vaccines which have effectively controlled the EV71 pandemic currently rely on inherent variable in vivo potency methods for batch release. To align with 3R (Replacement, Reduction, Refinement) principles and enhance quality control,...

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Xehetasun bibliografikoak

Egile Nagusiak:	Xuanxuan Zhang, Li Yi, Dan Yu, Jun Li, Xintian Li, Xing Wu, Fan Gao, Qian He, Wenhui Wang, Kaiwen Wang, Zejun Wang, Zhengling Liu, Yadong Li, Yong Zhao, Huiyi Li, Xiao Ma, Qingbing Zheng, Longfa Xu, Tong Cheng, Rui Zhu, Jing Guo, Jing Li, Qunying Mao, Zhenglun Liang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2025-04-01
Saila:	Vaccines
Gaiak:	enterovirus 71 inactivated vaccine in vitro relative potency in vivo potency correlation replacement
Sarrera elektronikoa:	https://www.mdpi.com/2076-393X/13/4/404
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