Nanopore full length 16S rRNA gene sequencing increases species resolution in bacterial biomarker discovery

Abstract Discovery of disease-related bacterial biomarkers could be a useful approach for early prevention or diagnosis of various afflictions, such as colorectal cancer. This typically involves analyzing small regions of the 16S rRNA gene (e.g. V3V4) through short-read technologies like Illumina, o...

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Dades bibliogràfiques
Autors principals: Pablo Aja-Macaya, Kelly Conde-Pérez, Noelia Trigo-Tasende, Elena Buetas, Mohammed Nasser-Ali, Paula Nión, Soraya Rumbo-Feal, Susana Ladra, Germán Bou, Álex Mira, Juan A. Vallejo, Margarita Poza
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-07-01
Col·lecció:Scientific Reports
Matèries:
Illumina
Oxford Nanopore
Colorectal cancer
16S rRNA
Biomarkers
Gut microbiome
Accés en línia:https://doi.org/10.1038/s41598-025-10999-8
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