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Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin.

Bordetella pertussis, the causative agent of whopping cough, produces an adenylate cyclase toxin (CyaA) that plays a key role in the host colonization by targeting innate immune cells which express CD11b/CD18, the cellular receptor of CyaA. CyaA is also able to invade non-phagocytic cells, via a uni...

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Príomhchruthaitheoirí: Christelle Angely, Daniel Ladant, Emmanuelle Planus, Bruno Louis, Marcel Filoche, Alexandre Chenal, Daniel Isabey
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2020-01-01
Sraith:PLoS ONE
Rochtain ar líne:https://doi.org/10.1371/journal.pone.0228606
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