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Selective alterations of neurons and circuits related to early memory loss in Alzheimer's disease

A progressive loss of episodic memory is a well-known clinical symptom that characterizes Alzheimer’s disease (AD). The beginning of this loss of memory has been associated with the very early, pathological accumulation of tau and neuronal degeneration observed in the entorhinal cortex (EC). Tau-rel...

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Hoofdauteurs: María eLlorens-Martín, Lidia eBlazquez-Llorca, Ruth eBenavides-Piccione, Alberto eRabano, Felix eHernandez, Jesus eAvila, Javier eDeFelipe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2014-05-01
Reeks:Frontiers in Neuroanatomy
Onderwerpen:
Cerebral Cortex
Dendritic Spines
Neurogenesis
Pyramidal Cells
granule cells
hippocampal connections
Online toegang:http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00038/full
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