Milvexian: An Oral, Bioavailable Factor XIa Inhibitor

Abstract Direct oral anticoagulants have a dose-dependent increased bleeding risk which limits use in certain populations. Studies in both animals and humans with inherited variations in factor XI levels provide a theoretical basis for a drug target capable of addressing current unmet needs. Milvexi...

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書誌詳細

主要な著者:	Shyon Parsa, Sneha S. Jain, Olu Akinrimisi, Carolyn S. P. Lam, Kenneth W. Mahaffey
フォーマット:	Artigo
言語:	Inglês
出版事項:	Adis, Springer Healthcare 2024-08-01
シリーズ:	Cardiology and Therapy
主題:	Milvexian Factor XI Anticoagulation Venous thromboembolism Hemostasis AXIOMATIC trials
オンライン･アクセス:	https://doi.org/10.1007/s40119-024-00379-0
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