Comparative analysis of ALA mediated sonodynamic therapy considering tumor size, light combination and ultrasound delivery in murine cutaneous melanoma

Abstract Sonodynamic therapy (SDT) is a non-invasive alternative treatment for cancer. However, its effects on early-stage and intradermally implanted melanoma remain underexplored. Here, we investigated the in vivo effects of 5-aminolevulinic acid (ALA)-mediated SDT on early-stage murine cutaneous...

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Hauptverfasser:	Erika Toneth Ponce Ayala, Iago Silva e Carvalho, Camila Aparecida Antunes, Aisha Mahmood, Michelle Barreto Requena, Fernanda Alves, Layla Pires, Vladislav Yakovlev, Vanderlei Salvador Bagnato, Sebastião Pratavieira
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-08-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Sonodynamic Photodynamic 5-aminolevulinic acid Protoporphyrin IX Melanoma
Online-Zugang:	https://doi.org/10.1038/s41598-025-16366-x
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