CRISPR-FMC: a dual-branch hybrid network for predicting CRISPR-Cas9 on-target activity
IntroductionAccurately predicting the on-target activity of sgRNAs remains a challenge in CRISPR-Cas9 applications, due to the limited generalization of existing models across datasets, small-sample settings, and complex sequence contexts. Current methods often rely on shallow architectures or unimo...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Genome Editing |
| Assuntos: | |
| Acceso en liña: | https://www.frontiersin.org/articles/10.3389/fgeed.2025.1643888/full |
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