Synthesis and Evaluation of Some 17-Acetamidoandrostane and N,N-Dimethyl-7-deoxycholic Amide Derivatives as Cytotoxic Agents: Structure/Activity Studies

Using pregnenolone and 7-deoxycholic acid as starting materials, some 17-acetamidoandrostane and N,N-dimethyl-7-deoxycholic amide derivatives were synthesized. The cytotoxicity of the synthesized compounds was tested in vitro against two tumor cell lines: SGC 7901 (human gastric carcinoma) and Bel 7...

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Principais autores:	Aimin Zhou, Chun Zeng, Huacan Song, Chunfang Gan, Linyi Jia, Jianguo Cui, Yanmin Huang
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2013-06-01
Series:	Molecules
Assuntos:	pregnenolone 17-acetamidoandrostane N,N-dimethyl-7-deoxycholic amide antiproliferative activity
Acceso en liña:	http://www.mdpi.com/1420-3049/18/7/7436
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