Vidarabine, an anti-herpes agent, improves Porphyromonas gingivalis lipopolysaccharide-induced cardiac dysfunction in mice

Abstract In this work, we examined the involvement of type 5 adenylyl cyclase (AC5) in cardiac dysfunction induced in mice given Porphyromonas gingivalis lipopolysaccharide (PG-LPS) at a dose equivalent to the circulating levels in periodontitis (PD) patients. Cardiac function was significantly decr...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Michinori Tsunoda, Ichiro Matsuo, Yoshiki Ohnuki, Kenji Suita, Misao Ishikawa, Takao Mitsubayashi, Aiko Ito, Yasumasa Mototani, Kenichi Kiyomoto, Akinaka Morii, Megumi Nariyama, Yoshio Hayakawa, Kazuhiro Gomi, Satoshi Okumura
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-08-01
coleção:	Journal of Physiological Sciences
Assuntos:	β-Adrenergic signaling Periodontitis Adenylyl cyclase Apoptosis Fibrosis Signal transduction
Acesso em linha:	https://doi.org/10.1186/s12576-023-00873-5
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!