Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway

The objective of this study was to investigate the molecular response to damage at the blood-brain barrier (BBB) and to elucidate critical pathways that might lead to effective treatment in central nervous system (CNS) pathologies in which the BBB is compromised. We have used a human, stem-cell deri...

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Detalhes bibliográficos

Principais autores:	Daniel Rand, Orly Ravid, Dana Atrakchi, Hila Israelov, Yael Bresler, Chen Shemesh, Liora Omesi, Sigal Liraz-Zaltsman, Fabien Gosselet, Taber S. Maskrey, Michal Schnaider Beeri, Peter Wipf, Itzik Cooper
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-02-01
coleção:	Pharmaceutics
Assuntos:	blood-brain barrier iron DFO HIF2A Ve-cadherin
Acesso em linha:	https://www.mdpi.com/1999-4923/13/3/311
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