Empagliflozin Attenuates Cardiac Fibrosis by Suppressing Fibroblast‐Mediated C‐C Motif Chemokine Ligand 2 Expression

Background Despite recent advances in pharmacotherapy, heart failure (HF) remains a major cause of hospitalization and death, particularly among aging populations. Sodium–glucose cotransporter 2 inhibitors have reduced hospitalization for HF and cardiovascular death. However, the mechanisms underlyi...

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Hlavní autoři:	Eri Nakai, Keita Horitani, Hayato Ogawa, Kensaku Wada, Yoshimitsu Yura, Kyung‐Duk Min, Sho Morioka, Yoshinobu Suwa, Ichiro Shiojima
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2026-02-01
Edice:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Témata:	chemokine ligand empagliflozin fibrosis heart failure macrophage polarization inhibitor
On-line přístup:	https://www.ahajournals.org/doi/10.1161/JAHA.125.043917
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