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Cerebrospinal fluid NPTX2/p‐tau ratio as a biomarker for cognitive decline in neurodegenerative diseases

Abstract INTRODUCTION Neuronal pentraxin 2 (NPTX2) and its use as a ratio with other synaptic proteins has emerged as a prognostic cerebrospinal fluid (CSF) biomarker across neurodegenerative diseases. METHODS Using a single molecule array (Simoa) method, CSF NPTX2 was measured in 688 individuals fr...

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Asıl Yazarlar: Bárbara Fernandes Gomes, Mathias Sauer, Laia Montoliu‐Gaya, Maria Franquesa‐Mullerat, Alexandre Bejanin, Daniel Alcolea, Alberto Lleó, Ignacio Illán‐Gala, Juan Fortea, Kaj Blennow, Henrik Zetterberg, Johanna Nilsson, Olivia Belbin, Nicholas J. Ashton
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2026-04-01
Seri Bilgileri:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Konular:
Alzheimer's disease
cerebrospinal fluid
cognitive decline
dementia with Lewy bodies
frontotemporal lobar degeneration
neuronal pentraxin 2
Online Erişim:https://doi.org/10.1002/dad2.70391
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