Adverse outcomes in SARS-CoV-2–infected pregnant mice are gestational age–dependent and resolve with antiviral treatment

SARS-CoV-2 infection during pregnancy is associated with severe COVID-19 and adverse fetal outcomes, but the underlying mechanisms remain poorly understood. Moreover, clinical studies assessing therapeutics against SARS-CoV-2 in pregnancy are limited. To address these gaps, we developed a mouse mode...

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Detalhes bibliográficos

Principais autores:	Patrick S. Creisher, Jamie L. Perry, Weizhi Zhong, Jun Lei, Kathleen R. Mulka, W. Hurley Ryan III, Ruifeng Zhou, Elgin H. Akin, Anguo Liu, Wayne Mitzner, Irina Burd, Andrew Pekosz, Sabra L. Klein
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2023-10-01
coleção:	The Journal of Clinical Investigation
Assuntos:	Reproductive biology Therapeutics
Acesso em linha:	https://doi.org/10.1172/JCI170687
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