Pericardial irradiation dose may be strongly associated with grade 4 lymphopenia and affect prognosis in patients with locally advanced esophageal cancer receiving definitive concurrent chemoradiotherapy

Abstract Background The immune system may influence prognosis, and lymphopenia is a frequent side effect of concurrent chemoradiotherapy (CCRT). Radical irradiation for locally advanced esophageal cancer (LA‐EC) exposes significant vascular and heart volumes. In this study, we hypothesized that lymp...

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Автори:	Xianyan Chen, Xiaoman Tian, Xuanwei Zhang, Qianyue Deng, Min Wang, Xiaojuan Zhou, Yong Xu, Lin Zhou, Bingwen Zou, Yongmei Liu, Rui Ao, You Lu, Youling Gong
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Wiley 2023-09-01
Серія:	Thoracic Cancer
Предмети:	concurrent chemoradiotherapy immune‐checkpoint inhibitor locally advanced esophageal cancer lymphopenia pericardial irradiation
Онлайн доступ:	https://doi.org/10.1111/1759-7714.15057
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